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Strategy 3: Maximize Clinical Opportunities

Clinical opportunities will be maximized if we can assure program growth through effective partnerships with referring teams and OPOs to optimize all aspects of the transplant pathway including patient acceptance, waiting list management, pre-transplant recipient care, donor evaluation, and donor management.

To read more details about this strategy, download the full Transplant Resource Guide

This section has been reviewed and updated as of October 2018. To see past content, click on the Archive tab below.

  • Tools & Templates

    Resources

    • Best Practices in Living Kidney Donation Consensus Conference Executive SummaryDownload
    • Increasing Organ Acceptance Rates Through Data Review and Risk StratificationDownload – by Sandy Felty, Lynette Martin del Campo, Sharon Norfles
    • Reducing Financial Barriers to Live DonationDownload
    • AST Living Donor Consensus Statement – Download
    • New Kidney Waitlist Management Tool Access – UNet
    • Patient and Family Partnership Councils and Beyond Download

    Academic Journals

    • Consensus Conference on Best Practices in Live Kidney Donation: Recommendations to Optimize Education, Access, and Care. – Article – LaPointe Rudow, D., Hays, R., Baliga, P., Cohen, D., Cooper, et al. (2015) American Journal of Transplantation, 15(4), pp.914-922. https://doi.org/10.1111/ajt.13173.
    • A Clinical Tool to Risk Stratify Potential Kidney Transplant Recipients and Predict Severe Adverse EventsArticle – Nygaard, R., Sirany, A., Wyman, E., Bodner, J., et al. (2016). Clinical Transplantation, 30(11), pp.1494-1500. https://doi.org/10.1111/ctr.12848
  • Policies
    • Organ Donation following Cardiac Death PolicyDownload – The Johns Hopkins Hospital
    • OPTN Policy 8 Download
    • Aligning OPTN Policies with the 2013 PHS Guideline for Reducing Transmission of HIV, HBV, and HCV through Solid Organ Transplantation – Download
  • Relevant Literature
    • A Comprehensive Risk Quantification Score for Deceased Donor Kidneys: The Kidney Donor Risk Index – Article – Rao PS, Schaubel DE, Guidinger MK, et al. (2009), Transplantation, 88(2): 231-236. https://doi.org/10.1097/TP.0b013e3181ac620b.
    • A Risk Prediction Model for Delayed Graft Function in the Current Era of Deceased Donor Renal Transplantation – Article – Irish WD, Ilsley JN, Schnitzler MA, et al. (2010), Am J Transplant, 10(10): 2279-2286. https://doi.org/10.1111/j.1600-6143.2010.03179.x.
    • A Simplified Donor Risk Index for Predicting Outcome After Deceased Donor Kidney Transplantation – Article – Watson CJ, Johnson RJ, Birch R, et al. (2012), Transplantation, 93(3): 314-318. https://doi.org/10.1097/TP.0b013e31823f14d4.
    • An Analysis of the Lack of Donor Pancreas Utilization From Younger Adult Organ Donors – Article – Wiseman AC, Wainright JL, Sleeman E, et al. (2010), Transplantation, 90(5): 475-480. https://doi.org/10.1097/TP.0b013e3181e9fea4.
    • Age Alone is Not a Contraindication to Kidney Donation: Outcomes of Donor Nephrectomy in the ElderlyArticle – Serrano, O., Yadav, K., Bangdiwala, A., Vock, D., Dunn, T., Finger, E., Pruett, T., Matas, A. and Kandaswamy, R. (2018). Clinical Transplantation, 32(8), p.e13287. https://doi/ 10.1111/ctr.13287.
    • Association of Candidate Removals From the Kidney Transplant Waiting List and Center Performance OversightArticle – Schold, J., Buccini, L., Poggio, E., Flechner, S. and Goldfarb, D. (2016). American Journal of Transplantation, 16(4), pp.1276-1284. https://doi.org/10.1111/ajt.13594.
    • Changes in Utilization and Discard of HCV-Antibody Positive Deceased-Donor Kidneys in the Era of Direct-Acting Antiviral Therapy Article (subscription) – Bowring, M., Kucirka, L., Massie, A., Ishaque, T., Bae, S., Shaffer, A., Wang, J., Sulkowski, M., Desai, N., Segev, D. and Durand, C. (2018). Transplantation, p.1. https://doi.org/10.1097/TP.0000000000002323.
    • Comparison of Recipient Outcomes Following Transplant From Local Versus Imported Pancreas Donors – Article – Finger EB, Radosevich DM, Bland BJ, et al. (2012), Am J Transplant, 12(2): 447-457. https://doi.org/10.1111/j.1600-6143.2011.03828.x. Epub 2011 Nov 9. 
    • Cost-effectiveness of Transplanting HCV-Infected Livers into Uninfected Recipients with Preemptive Antiviral Therapy Article (subscription) – Bethea, E., Samur, S., Kanwal, F., Ayer, T., et al. (2018). Clinical Gastroenterology and Hepatology. https://doi.org/10.1016/j.cgh.2018.08.042.
    • Direct-Acting Antiviral Prophylaxis in Kidney Transplantation From Hepatitis C Virus–Infected Donors to Noninfected Recipients Article (subscription) – Durand, C., Bowring, M., Brown, D., Chattergoon, M., Massaccesi, G., Bair, N., Wesson, R., Reyad, A., Naqvi, F., Ostrander, D., Sugarman, J., Segev, D., Sulkowski, M. and Desai, N. (2018). Annals of Internal Medicine, 168(8), p.533. https://doi.org/10.7326/M17-2871.
    • Donor Brain Death Time and Impact on Outcomes in Heart Transplantation – Article – Marasco S, Kras A, Schulberg E, et al. (2013), Transplant Proc, 45(1): 33-37. https://doi.org/10.1016/j.transproceed.2012.08.008. 
    • Donor Predictors of Allograft Use and Recipient Outcomes After Heart Transplantation – Article – Khush KK, Menza R, Nguyen J, et al. (2013), 6(20): 300-309. https://doi.org/10.1161/CIRCHEARTFAILURE.112.000165. Epub 2013 Feb 7.
    • Donor risk score and baseline biopsy CADI value predict kidney graft outcome – Article – Kahu J, Kyllönen L, Räisänen-Sokolowski A, Salmela K. (2011), Clin Transplant, 25(3): E276-283. https://doi.org/10.1111/j.1399-0012.2011.01401.x. Epub 2011 Feb 9.
    • Extended-Criteria Donors in Liver Transplantation Part II: Reviewing the Impact of Extended-Criteria Donors on the Complications and Outcomes of Liver TransplantationArticle (subscription) -Nemes, B., Gámán, G., Polak, W., Gelley, F., Hara, T., et al. (2016). Expert Review of Gastroenterology & Hepatology, 10(7), pp.841-859. https://doi.org/10.1586/17474124.2016.1149062.
    • Factors Associated With Primary Graft Failure After Heart Transplantation – Article – Russo MJ, Iribarne A, Hong KN, et al. (2010), Transplantation, 90(40: 444-450. https://doi.org/10.1097/TP.0b013e3181e6f1eb.
    • Frailty is Independently Associated with Increased Hospitalization Days in Patients on the Liver Transplant WaitlistArticle – Sinclair, M., Poltavskiy, E., Dodge, J. and Lai, J. (2017). World Journal of Gastroenterology, 23(5), p.899. https://doi.org/10.3748/wjg.v23.i5.899.
    • Geographic Disparities in Donor Lung Supply and Lung Transplant Waitlist Outcomes: A Cohort Study – Article – Benvenuto, L., Anderson, D., Kim, H., Hook, J., Shah, L., Robbins, H., D’Ovidio, F., Bacchetta, M., Sonett, J. and Arcasoy, S. (2018). American Journal of Transplantation, 18(6), pp.1471-1480. https://doi.org/10.1111/ajt.14630.
    • Hepatitis C Transmission from Seropositive, Nonviremic Donors to Non-Hepatitis C Liver Transplant Recipients Article (subscription) –  Bari, K., Luckett, K., Kaiser, T., Diwan, T., et al. (2018). Hepatology, 67(5), pp.1673-1682. https://doi.org/10.1002/hep.29704
    • How to Recognize a Suitable Pancreas Donor: A Eurotransplant Study of Preprocurement Factors – Article – Vinkers MT, Rahmel AO, Slot MC, et al. (2008), Transplant Proc, 40(50): 1275-1278. https://doi.org/10.1016/j.transproceed.2008.03.142. 
    • Impact of High-Dose Inotropic Donor Support on Early Myocardial Necrosis and Outcomes in Cardiac Transplantation – Article – Nixon JL, Kfoury AG, Brunisholz K, et al. (2012), Clin Transplant, 26(2): 322-327. https://doi.org/10.1111/j.1399-0012.2011.01504.x. Epub 2011 Oct 10. 
    • Improving Pancreas Graft Utilization Through Importation Article (subscription)– – Torabi, J., Rocca, J., Choinski, K., Lorenzen, K., Yongue, C., Lubetzsky, M., et al. (2017). Clinical Transplantation, 32(1), p.e13154. https://doi.org/10.1111/ctr.13154.
    • International Liver Transplant Society Practice GuidelinesArticle (subscription) – Krowka, M., Fallon, M., Kawut, S., Fuhrmann, V., Heimbach, J., Ramsay, M., Sitbon, O. and Sokol, R. (2016). Transplantation, 100(7), pp.1440-1452. https://doi.org/10.1097/TP.0000000000001229.
    • Living Donor Liver Transplantation: Eliminating the Wait for Death in End-Stage Liver Disease?Article (subscription) – Fisher, R. (2017). Nature Reviews Gastroenterology & Hepatology, 14(6), pp.373-382. https://doi.org/10.1038/nrgastro.2017.2.
    • Machine Perfusion or Cold Storage in Deceased-Donor Kidney Transplantation – Article – Moers C, Smits JM, Maathuis MH, et al. (2009), N Engl J Med, 360(1): 7-19. https://doi.org/10.1056/NEJMoa0802289.
    • Machine Perfusion or Cold Storage in Deceased-Donor Kidney Transplantation- Letter to the Editor – Article – Moers C, Pirenne J, Paul A, Ploeg RJ. (2012), N Engl J Med, 366: 770-771. https://doi.org/10.1056/NEJMc1111038.
    • Machine Perfusion Versus Cold Storage for the Preservation of Kidneys Donated After Cardiac Death: A multicenter, randomized, controlled trial – Article – Jochmans I, Moers C, Smits JM, et al. (2010), Ann Surg, 252(5): 756-764. https://doi.org/10.1097/SLA.0b013e3181ffc256.
    • Optimizing outcomes in pancreas transplantation: Impact of organ preservation time Article (subscription) – Rudolph, E., Dunn, T., Sutherland, D., Kandaswamy, R. and Finger, E. (2017). Clinical Transplantation, 31(9), p.e13035. https://doi.org/10.1111/ctr.13035.
    • Pancreas Transplantation From Donors After Cardiac Death: An Update of the UNOS Database – Article (subscription) – Siskind, E., Akerman, M., Maloney, C., Huntoon, K., Alex, A., et al. (2014). Pancreas, 43(4), pp.544-547. https://doi.org/10.1097/MPA.0000000000000084.
    • Preservation of the Donor Pancreas for Whole Pancreas and Islet Transplantation – Article – Ridgway D, Manas D, Shaw J, White S. (2010), Clin Transplant, 24(1): 1-19. https://doi.org/10.1111/j.1399-0012.2009.01151.x. Epub 2009 Dec 14.
    • Risk Factor Analysis of Late Survival After Heart Transplantation According to Donor Profile: A Multi-Institutional Retrospective Study of 512 Transplants – Article – Fiorelli AI, Branco JN, Dinkhuysen JJ, et al. (2012), Transplant Proc, 44(8): 2469-2472. https://doi.org/10.1016/j.transproceed.2012.07.025. 
    • Role of Perfusion Machines in the Setting of Clinical Liver Transplantation: A Qualitative Systematic Review – Article (subscription) – Lai, Q., Melandro, F., Rossi, M., Ruberto, F., Pugliese, F. and Mennini, G. (2018). Clinical Transplantation, 32(8), p.e13310. https://doi.org/10.1111/ctr.13310.
    • Systematic Evaluation of Pancreas Allograft Quality, Outcomes and Geographic Variation in Utilization – Article – Axelrod DA, Sung RS, Meyer KH, et al. (2010), Am J Transplant, 10(4): 837-845. https://doi.org/10.1111/j.1600-6143.2009.02996.x. Epub 2010 Feb 1.
    • The APOL1 Long-Term Kidney Transplantation Outcomes Network-APOLLOArticle – Freedman, B. and Moxey-Mims, M. (2018). Clinical Journal of the American Society of Nephrology, p.CJN.01510218. https://doi.org/10.2215/CJN.01510218.
    • Trial of Transplantation of HCV-Infected Kidneys into Uninfected RecipientsArticle – Goldberg, D., Abt, P., Blumberg, E., Van Deerlin, V., et al. (2017). New England Journal of Medicine, 376(24), pp.2394-2395. https://doi.org/10.1056/NEJMc1705221.
    • Utilization of Hepatitis C Virus RNA-Positive Donor Liver for Transplant to Hepatitis C Virus RNA-Negative RecipientArticle – Saberi, B., Hamilton, J., Durand, C., Li, Z., Philosophe, B., et al. (2017). Liver Transplantation, 24(1), pp.140-143. https://doi.org/10.1002/lt.24838.
    • What Is the Influence of Both Risk Donor and Risk Receiver on Simultaneous Pancreas-Kidney Transplantation? Article (subscription) – Sánchez-Hidalgo, J., Salamanca-Bustos, J., Arjona-Sánchez, Á., Campos-Hernández, J., et al. (2018). Transplantation Proceedings, 50(2), pp.664-668. https://doi.org/10.1016/j.transproceed.2017.09.065.
  • Archive

    Policies

    • Organ Donation Following Cardiac Death Policy Download – The Johns Hopkins Hospital

    Academic Journals

    • Liver Transplantation From Old Donors into HCV and Non-HCV RecipientsArticle (subscription) – Baccarani, U., Adani, G., Toniutto, P., Sainz, M., et al. (2004). Transplantation Proceedings, 36(3), pp.527-528. https://doi.org/10.1016/j.transproceed.2004.02.023.
The Alliance welcomes submissions to the Transplant Resource Guide & Tools.
Contributions can be emailed to info@odt-alliance.org with a statement providing approval for posting to this site.