Glowing urine may replace the biopsy needle: In detecting organ transplant rejection, a new nanoparticle has proven much faster and more thorough in the lab than a biopsy.

Posts Tagged 'T-cells'

Fluorescing urine signals organ transplant rejection, could replace needle biopsies

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Glowing urine may replace the biopsy needle: In detecting organ transplant rejection, a new nanoparticle has proven much faster and more thorough in the lab than a biopsy. When T cells mount their first attack on the organ’s cells, the nanoparticle sends an alarm signal into the urine that makes it fluoresce.

Too often, it’s only after a transplanted organ has sustained serious damage that a biopsy reveals the organ is in rejection. A new screening method using sensor particles and ...

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Key found to making transplant rejection a thing of the past?

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Houston Methodist researchers have cracked a code in T-cells that could make autoimmune diseases and organ transplant rejection a thing of the past.

Wenhao Chen, Ph.D., a scientist in the Immunobiology and Transplant Science Center at the Houston Methodist Research Institute, and his colleagues have identified a critical switch that controls T-cell function and dysfunction and have discovered a pathway to target it.

Their findings are described in an article titled “Ablation of Transcription Factor IRF4 Promotes Transplant Acceptance by Driving Allogenic ...

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