Posts Tagged 'kidney transplant'

‘Weekend Effect’ on Donor Kidney Discards?

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Philadelphia, PA, May 12, 2016 — Investigators have uncovered a “weekend effect” contributing to the worsening availability of donor kidneys in the United States. They found that kidneys that would normally be made available for transplantation were less likely to be procured from donors over the weekend (89.5% on the weekend vs. 90.2% during the week). Further, organs procured during the weekend were more than 20% more likely to be discarded than kidneys procured on other days, although the discarded ...

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Study Suggests Reduced Immunosuppression May Be Best

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The kidney is the most commonly transplanted organ in the United States, with more than 17,000 transplants performed each year. Following kidney transplant, patients are routinely placed on a regimen of immunosuppressant medications to prevent organ rejection, which often includes calcineurin inhibitors (CNIs) as the backbone medication of this regimen. However, questions remain about the best use of these drugs to strike the balance between preventing rejection and avoiding drug-related complications. Researchers from the Perelman School of Medicine at the ...

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Education Corner – HIV and Organ Donation & Transplantation

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 Current Situation

  • 10-30% of the human immunodeficiency virus (HIV) infected population, develop chronic kidney disease (CKD) (Lucas et al, 2014).
  • This population accounts for about 1.5% of the dialysis population.
  • There was a 14-fold increase in prevalence between 1999 and 2010.

 The Development of the HOPE Act

  • With the ongoing organ shortage, novel donor sources are needed.
  • In 1984 & 1988, the National Organ Transplant Act, made the following provision: 42 U.S.C. 274(b) Sect 372(b):

“…requires the OPTN to adopt and use standards for preventing ...

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New Rules Bringing Kidneys to Hardest-to-Transplant Patients

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A shake-up of the nation’s kidney transplant system means more organs are getting to patients once thought nearly impossible to match, according to early tracking of the new rules.

It’s been a year since the United Network for Organ Sharing changed rules for the transplant waiting list, aiming to decrease disparities and squeeze the most benefit from a scarce resource: kidneys from deceased donors. Now data from UNOS shows that the changes are helping certain patients, including giving those expected to ...

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Kidney Tissue Grown in Lab

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Scientists from Australia and the Netherlands say they have grown rudimentary human kidney tissue from stem cells. This presents a step forward to growing a fully-functional, lab-made organ for transplant. The tissue is not yet a viable organ, but may be useful for other purposes such as for an alternative to animals in drug toxicity testing. The researchers grew their “kidney-like structure” from induced pluripotent stem (iPS) cells, which are adult cells reprogrammed into a neutral state from which they ...

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First Kidney Transplants in Ethiopia Supported by U-M

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After spending more than two years to help to establish a transplant program, the University of Michigan (U-M) team helps St. Paul’s Hospital Millennium Medical College in Ethiopia perform their first kidney transplants. U-M Transplant Surgeon Jeffrey D. Punch, MD led a team that did three kidney transplants in Addis Ababa, Ethiopia. All three transplants were from living donors and all recipients and donors are doing well.

This collaboration started through the initiative of Senait Fisseha, M.D, J.D., an adjunct professor ...

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First Transplant in the World for a Unique Patient

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Brad Jordan, 24 years, and Bri Jordan, his older sister, were born with primordial dwarfism. According to Dr. Craig Langman, for patients with primordial dwarfism, the bone cells generally do not develop after birth or by the end of the first year of their life. It is a genetic mutation which also impacts the blood vessels, causing them to be weakened, and placing patients with this condition at higher risk for brain aneurysms. Brad has undergone three life-saving neurosurgeries and ...

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Kidney is Focus of 3rd SOS Science Summit

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High incidences of uncontrolled high blood pressure and obesity-linked diabetes are large driving factors for kidney disease which is reaching an epidemic level, according to entities such as the Centers for Disease Control and the National Institutes for Health.

Of the 123,231 patients waiting for organ transplants, 101,699 are waiting for kidney transplants, yet only about 28,500 – 29,500 kidneys are transplanted each year, which is not making gains with the growth of the list. (Data retrieved from www.unos.org.)

To address ...

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Positive Survival Rates Among Mono-Infected HIV+ Kidney Recipients

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A study in the Journal of the American Society of Nephrology reports the results of an examination of U.S. HIV+ kidney transplant recipients compared to non-HIV+ recipients from 2002-2011.

The 5- and 10-year graft survival rates were significantly lower among HIV+ recipients when compared to those with no HIV. However, when the mono-infected HIV+ recipient data was separated from those who had both HIV and HCV (hepatitis C virus), the survival rate was comparable to the non-infected recipients.

 

Read more at http://medicalxpress.com/news/2015-03-excellent-outcomes-hiv-kidney-transplant.html
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SF Surgeons Complete 12 Surgeries in 6-Way Kidney Transplant Chain

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The California Pacific Medical Center carried out the largest kidney donation chain in the 44-year history of the hospital’s transplant center by coordinating 6 kidney transplants through a 6-way patient-donor swap. This is like a Domino-like kidney swap when a living donor’s kidney is incompatible with a relative or friend who needs one and they are paired up with others in the same situation.

Read more at: http://sanfrancisco.cbslocal.com/2015/03/06/surgeons-complete-kidney-transplants/
http://news.yahoo.com/kidney-donation-triggers-transplant-chain-san-francisco-141020328.html

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