Posts Tagged 'kidney transplant'

Small Steps, Big impact – 3D Bioprinting Kidneys at Harvard

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Though it takes just an instant for research to become a discovery, an apple falling from a tree; a bolt of lighting; the snap of a shutter, fully developed breakthroughs in science and medicine take years to perfect, and what we read now, about Harvard material scientists’ developments in the bioprinting of a kidney structure, is one small step closer to a future where organ transplant lists are a thing of the past.

A paper published on 11th October 2016, entitled ...

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DNA Scoring System Could Improve Kidney Transplant Matching

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Doctors currently rely on several criteria including three main blood tests, cell surface tests and limited DNA tests to determine if a patient and a potential donor are a kidney match.

But the system is far from flawless. While transplant survival rates for patients with end stage renal failure are higher than for those treated with dialysis, 40% to 50% of kidney transplants still fail within 10 years.

Now scientists have come up with a comprehensive DNA scoring system using many genes ...

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New Bill Introduced to Extend Immunosuppressive Coverage for Transplant Patients

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On Sept. 22, Representatives Michael C. Burgess, MD, R-Texas, and Ron Kind, D-Wisc., introduced the Immunosuppressive Drug Coverage for Kidney Transplant Patients Act. This legislation would allow individuals who are eligible for immunosuppressive drugs under Medicare Part B to continue to receive their treatment past the current 36-month cutoff.

Currently, Medicare beneficiaries who are 65 or older or who are receiving Social Security Disability Income are covered under Part B for their immunosuppressive drugs without any time limitation. Under the proposed ...

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First Clinical Trial Transplants Hepatitis C-Infected Kidneys

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Patients who need a kidney transplant may have new hope, through an innovative Penn Medicine clinical trial using kidneys from deceased donors who had the Hepatitis C virus (HCV). The first study participant received a kidney transplant in July 2016, and after being treated with a full regimen of Zepatier – a recently-approved oral medication prescribed to eradicate HCV – her doctors announced today that there is no evidence of the virus in her blood. Irma Hendricks of East Stroudsburg, ...

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Patients Undergo Britain’s First Robotic Kidney Transplants

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Two patients have made unprecedentedly speedy recoveries after becoming the first in Britain to have kidney transplants carried out by a robot. Surgeons at Guy’s and St Thomas’ NHS Foundation Trust in London controlled the machine as it sewed up the patients’ kidneys through precise keyhole incisions in the body. The robot performed the transplants so meticulously and caused such limited damage to surrounding tissue that the patients were able to leave the hospital after just four days, needing only paracetamol to ...

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Post-Transplant Decrease in Kidney Graft Size Predicts Worse Outcomes

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A decrease rather than an increase in kidney graft size during the first year after deceased-donor kidney transplantation strongly predicts subsequent graft dysfunction, new findings suggest.

Compared with transplant recipients who experienced an increase in graft size, those who had a decrease had a significant 4.5 times higher risk of a composite outcome of a 50% or greater reduction in estimated glomerular filtration rate (eGFR) or end-stage graft failure during the first year post-transplant in adjusted analyses, researchers reported in Transplantation ...

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Vanderbilt Surgeons Perform Historic Double Transplant on Man Over 70

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For a long time, doctors followed stringent guidelines over who can receive vital organ transplants. “We used to have these hard and fast rules about age,” said Dr. Ashish Shah, a cardiac surgeon at Vanderbilt University Medical Center.

But Rex and Nancy Parton are changing that dialogue. Multiple doctors told them that because Rex is over the age of 70, typically the cut-off age for a heart or kidney transplant, there was nothing more they could do for him. The Partons ...

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Landmark Research Helps Predict Kidney Transplant Organ Failure Risk

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Australian and American researchers have identified several genes that hold the key to determining the future outcome of a kidney transplant, in what has been described as a landmark breakthrough in medical research. The lead author of the study published in The Lancet medical journal, Professor Philip O’Connell, said the discovery meant people could get treatment before irreversible damage had occurred.

“If we get people a transplant, and get that transplant to live longer, then we have less people on dialysis, less ...

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Kidney Transplant Recipients with Inflammation Prior to Surgery More Likely to Develop Diabetes

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Up to 30 percent of people who receive organ transplants will develop diabetes, but researchers are unsure why. Although doctors typically blame immunosuppressive drugs that transplant recipients take to prevent organ rejection, it’s unclear why some people develop the lifelong disorder, while others do not. A new study in kidney transplant recipients suggests that patients with more inflammation prior to surgery are more likely to develop diabetes than those with less overall inflammation, and that a patient’s fat stores also ...

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Finding Organ Donors Concealed in Plain Sight

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Last June, after it became clear that their 3-month-old son, Nathan, needed a liver transplant, Rob and Christina Whitehead of Mokena, III., created a Facebook page to tell his story. Word spread quickly. “More than a hundred people called our donor hotline,” recalled Talia B. Baker, director of the Living Donor Liver Transplant program at Northwestern University Feinberg School of Medicine. In August, Nathan received a transplant. He’s had some complications, but nine months later, videos show him cruising happily ...

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