Posts Tagged 'innovation'

World’s First 3-D Printed Tibia Transplanted

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Surgeons in Australia have successfully performed a world-first transplant surgery, installing a 3D printed tibia into the leg of Reuben Lichter, who faced losing his leg above the knee to amputation. The 3D printed tibia was wrapped in blood vessels and leg tissue from both of his legs. Just over two weeks ago, in the last in a series of five surgeries, the procedure was declared a success. For the next nine months at least, the doctors hope to observe ...

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Education Corner – Developing Advances in Organ Transplantation: Organ Banking – What is it?

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Developing Advances in Organ Transplantation: Organ Banking – What is it?

A New World?

Imagine a world where no one who needs an organ transplant has to wait for an organ to become available. A transplant in this new world would be a scheduled surgery. Families who want the donation process to occur quickly could easily be accommodated, as the organs can be recovered and banked until the right ...

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Researchers discover indicator of lung transplant rejection

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Research by scientists at Dignity Health St. Joseph’s Hospital and Medical Center’s Norton Thoracic Institute was published in the July 12, 2017 issue of Science Translational Medicine titled, “Zbtb7a induction in alveolar macrophages is implicated in anti-HLA-mediated lung allograft rejection.”

This research was conducted at the laboratories of Thalachallour Mohanakumar, PhD and Deepak Nayak’s PhD at the Norton Thoracic Institute in Phoenix, Ariz. The labs are dedicated to the understanding of immunologic reactions leading to graft rejection following human lung transplantation.

Lung transplantation, where diseased lungs ...

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Scientists develop first app and method to predict heart events after liver transplant

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The first app and score to determine the one-year risk of a liver transplant patient dying or being hospitalized for a heart attack or other cardiovascular complication has been developed by Northwestern Medicine scientists.

“Knowing the patient’s risk is critical to help prevent the frequent cardiac complications that accompany liver transplant surgery and to determine which patients are likely to survive the transplant,” said Dr. Lisa VanWagner, an assistant professor of medicine and preventive medicine at Northwestern University Feinberg School of ...

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New study suggests many discarded kidneys could prolong life

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The results of a new study suggest that high discard rates among donated kidneys could be avoided in the future. Researchers say that even kidneys with poor biopsy results may be more efficient in prolonging patients’ lifespans than other treatments.

According to the Organ Procurement and Transplantation Network (OPTN), so far this year, 6,099 kidneys have been donated in the United States. Of these, living donors provided 2,223 kidneys, with the remaining 3,876 having been collected from deceased ...

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Could donor organs be frozen to save lives later?

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Long-term preservation of donor organs and tissue for on-demand transplants and medical procedures sounds futuristic — something of the medical ideal.

Need a heart or kidney transplant? Just grab one from the freezer. But, hey, the Arctic wood frog thaws and reanimates each year after being frozen for 240 days, so why can’t the same be done for human hearts, lungs and livers?

Such research, long underway with success in preserving skin tissue and heart valves, largely has remained off the radar, ...

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CNBC reports on new technology to combat organ shortage

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Every year, tens of thousands of Americans receive new organs, giving them a new lease on life when the ones they were born with start to fail. In 2016 there were more than 33,600 transplants, a number that has risen by 20 percent in the past five years.

However, there are many more than that waiting on the transplant list — about 120,000 people total. Sometimes they wait for years; an average of about Continue Reading →

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World-first quintuple organ transplant performed in Australia

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Stephanie Dundas’ body was so full of other people’s DNA that even her doctors had secretly given up hope of finding a match for the five new organs needed to save her life.

A previous liver transplant and years of regular blood transfusions meant the 27-year-old carried so many antibodies she was incompatible with more than 98 percent of potential organ donors.

But now Stephanie, 26, is recovering as the first cystic fibrosis patient in the world to receive a quintuple organ transplant, ending ...

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New UNOS kidney allocation system narrowed racial gaps in transplant

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A new kidney allocation system implemented in 2014 by the United Network for Organ Sharing reduced racial disparities in receipt of kidney transplants, according to a study published in the June issue of Health Affairs.

Taylor A. Melanson, from Emory University in Atlanta, and colleagues examined the effect of the new kidney allocation system implemented in 2014 on racial disparities in receipt of kidney transplant. Data were analyzed for 179,071 transplant waiting list events from June 2013 to September 2016, and ...

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Danish boy undergoes experimental thymus transplant surgery

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The thymus is a small glandular structure that regulates the immune system. Without this vital organ, a baby will often die within the first year from a simple bacterial or viral infection.

Three years ago, Marianne Ifversen, a Danish senior doctor at Rigshospital, found out that a boy brought in to see her didn’t have one. Fortunately, this is an extremely rare condition.

The boy is now one of 12 European children who have received experimental transplant surgery to remedy this deficiency, ...

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