Hepatitis C-positive Heart Transplants: Safer After All?

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As of July 5, 2018, there are 3,960 people in the United States on the waitlist for a heart transplant. That’s only a fraction of the 114,554 people who need organ transplants. There is a great need for organ donations, and physicians at the University of Washington Medical Center have initiated a protocol to help with that.

The UW heart transplant team, led by Dr. Jason Smith, the associate surgical director of heart transplantation and a cardiac surgeon, plans to transplant hearts from ...

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Study to look at extending heart transplantation donor pool

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With $4 million in funding from the Brockman Medical Research Foundation, surgeons and scientists at Baylor College of Medicine and the Texas Heart Institute will study the utility of previously unused organs to increase the number of heart transplantations, potentially making transplant possible for thousands of patients who die while waiting for an acceptable heart to become available.

“Only 3,000 heart transplants are performed annually and several thousand people with end-stage heart failure who are on the waitlist and could benefit from a ...

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Post-heart transplant cancer rates are climbing

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More than 10 percent of heart transplant recipients developed cancer between one and five years post-transplantation—most commonly skin cancer—according to a study published in the Journal of the American College of Cardiology.

Survival in transplant patients with de novo malignancy—the first occurrence of cancer in the body—is markedly shorter than those with no malignancy, reported lead author Jong-Chan Youn, MD, PhD, and colleagues.

“Importantly, the increased risk of mortality was sizeable even for patients diagnosed with skin cancer; this finding is in contrast to the ...

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50 Years Ago This Week: Inside the First Heart Transplant

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It was a medical breakthrough generations in the making. For as long as doctors had understood the crucial role of the heart, they had dreamed of using transplants to save people whose heart problems would otherwise doom them to death. Earlier attempts, especially before the discovery of blood types, had failed. Now, in late 1967, there were suddenly not one but two real-life examples to point to.

Though one of the operations (a transplant between babies, in Brooklyn) failed, the other ...

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DAAs prove effective for HCV-infected heart transplant patients

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Direct-acting antiviral (DAA) drugs proved safe and effective for hepatitis C (HCV) patients who had undergone heart transplants, according to new research.

Jia-Horng Kao, MD, PhD, FAASLD, and a team from the National Taiwan University Hospital in Taipei, found that 12 individuals given sofosbuvir combined with ledipasvir (Harvoni) or sofosbuvir (Sovaldi) combined with daclatasvir (Daklinza) achieved a sustained virologic response rate of 100% after 12 weeks.

Interferon-free DAAs have shown excellent efficacy and safety for ordinary patients with chronic HCV infection, the researchers ...

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Loyola Medicine Performs 800th Heart Transplant

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A grandfather from Hanover Park, Illinois recently became the 800th patient to receive a heart transplant at Loyola University Medical Center.

“It was like winning the lottery,” said José Garcia, a 53-year-old industrial mechanic with three daughters and three grandchildren.

Loyola performed its first heart transplant on March 11, 1984 and has performed more heart transplants than any other center in Illinois. During the first 10 months of 2016, Loyola performed 29 heart transplants, which also is the highest in Illinois.

Read the ...

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Baptist Health Performs 250th Heart Transplant

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Twenty-seven years ago, Baptist Health was the first hospital in the state to perform a heart transplant and now celebrates the life-giving milestone of transplanting the 250th heart since the transplant program began in 1989.

Brittany Dow, 33, of Little Rock, received the 250th heart on Sunday, Oct. 2. She is listed in serious condition, which is to be expected at this time, at Baptist Health Medical Center-Little Rock (BHMC-LR). Dow was diagnosed with congestive heart failureand was on the transplant waiting ...

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University of Rochester Medicine Performs 200th Heart Transplant

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Cardiac surgeons at UR Medicine’s Strong Memorial Hospital recently performed a 200th heart transplant surgery, providing a 48-year-old father a second chance on life.

Transplant surgeons Juan Lehoux, M.D., surgical director of the Program in Heart Failure and Transplantation, and Sunil Prasad, M.D., performed the six-hour life-saving procedure Aug. 24 and Stephen Waite Jr. of Oswego is recovering at Strong Memorial Hospital.

Reaching this milestone is a proud moment for the heart failure and transplant team, an integral part of UR Medicine ...

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Vanderbilt Surgeons Perform Historic Double Transplant on Man Over 70

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For a long time, doctors followed stringent guidelines over who can receive vital organ transplants. “We used to have these hard and fast rules about age,” said Dr. Ashish Shah, a cardiac surgeon at Vanderbilt University Medical Center.

But Rex and Nancy Parton are changing that dialogue. Multiple doctors told them that because Rex is over the age of 70, typically the cut-off age for a heart or kidney transplant, there was nothing more they could do for him. The Partons ...

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Attenuated-signal Plaque Progression Predicts Long-term Mortality after Heart Transplantation

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In patients who had heart transplantation, attenuated-signal plaque progression may be an independent predictor of long-term mortality, researchers reported in the Journal of the American College of Cardiology. According to the study background, previous research on coronary atherosclerosis found associations between attenuated-signal plaque, plaque instability and adverse events.

Kozo Okada, MD, from the division of cardiovascular medicine, Stanford Cardiovascular Institute, Stanford University School of Medicine, and colleagues enrolled 105 patients who had survived at least 1 year after heart transplantation and had ...

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