Pediatric Donation

The Alliance welcomes submissions to the Organ Donation Toolbox.
Contributions can be emailed to info@odt-alliance.org with a statement providing approval for posting to this site.

This section has been reviewed and updated as of July 2018. To see past content, click on the Archive tab below.

  • Neonatal & Anencephalic Donation

    Academic Journals

    • Anencephalic Organ Donation after Cardiac Death: A Case Report on Practicalities and EthicsArticle (subscription) – Powers RJ, Schultz D, Jackson S. (2015) J Perinatol, 35(10):785-7. https://doi.org/10.1038/jp.2015.72
    • Death by Neurologic Criteria in a Neonate: Implications for Organ Donation Article (subscription) – Bokisa AE, et al. (2015) J Neonatal Perinatal Med, 8(3):263-7. https://www.doi.org/10.3233/NPM-15814074
    • Multi-visceral Transplantation Using a 2.9 kg Neonatal Donor Article (subscription) – P. Cauley, et al. (2012) Pediatric Transplant, 16(8):E379-82. https://doi.org/10.1111/j.1399-3046.2012.01739
    • Potential and Actual Neonatal Organ and Tissue Donation after Circulatory Determination of DeathArticle – Stiers, J. et al. (2015) JAMA Pediatrics, 169(7), p.639. https://www.doi.org/10.1001/jamapediatrics.2015.0317

    Resources

    • Neonatal Donation Family Brochure “The Journey…Creating a Legacy for Your Baby”Download – International Institute for the Advancement of Medicine
    • Neonatal Donation Guidelines and CommunicationDownload – International Institute for the Advancement of Medicine
    • Neonatal Fast Facts – Medical Research with Neonatal Organs and TissuesDownload – International Institute for the Advancement of Medicine
  • Pediatric Determination of Death

    Academic Journals

    • A Brain Death Dilemma: Apnea Testing While on High-Frequency Oscillatory VentilationDownload – Gilson N, Weisleder P, Ream MA. (2015) Pediatrics, 135(1):e5-6. https://doi.org/10.1542/peds.2014-2133. Epub 2014 Dec 8.
    • Developing a Standard Method for Apnea Testing in the Determination of Brain Death for Patients on Venoarterial Extracorporeal Membrane Oxygenation: A Pediatric Case Series Article (subscription) – Jarrah RJ, Ajizian SJ, Agarwal S, et al. (2014) Pediatric Critical Care Medicine, 15(2):e38-43. https://doi.org/10.1097/PCC.0000000000000006
    • Guidelines for the Determination of Brain Death in Infants and Children: An Update of the 1987 Task Force Recommendations – Download – Nakagawa T, Ashwal S, et al. (2011) Critical Care Med, https://doi.org/10.1542/peds.2011-1511
    • Pediatric Brain Death Determination Article (subscription) – Mathur M, Agarwal S. (2015) Semin Neurol, 35(2):116-24. https://doi.org/10.1055/s-0035-1547540. Epub 2015 Apr 3.
  • Pediatric Donation After Circulatory Death

    Academic Journals

    • Canadian Guidelines for Controlled Pediatric Donation after Circulatory Determination of Death – Summary ReportArticle (subscription) – Weiss MJ, Hornby L, Rochwerg B, et al. (2017),Pediatric Critical Care Medicine, 18(11):1035-1046. https://doi.org/10.1097/PCC.0000000000001320
    • Development of a Bedside Tool to Predict Time of Death After Withdrawal of Life-Sustaining Therapies in Infants and Children Article (subscription) – Shore PM, Huang R, Roy L, et al. (2012) Pediatric Critical Care Medicine, 13(4):415-22. https://doi.org/10.1097/PCC.0b013e318238b830
    • Pediatric Donation after Circulatory Determination of Death: A Scoping Review – Article (subscription) – Weiss MJ, Hornby L, Witteman W, Shemie SD. (2016),Pediatric Critical Care Medicine, 17(3):e87-e108. https://doi.org/10.1097/PCC.0000000000000602
    • Pediatric Organ Donation and Transplantation – Download – Workman JK, Myrick CW, Meyers RL, Bratton SL, Nakagawa TA. (2013) Pediatrics, 131(6):e1723-30. https://doi.org/10.1542/peds.2012-3992. Epub 2013 May 20.
  • Pediatric Donor Management

    Academic Journals

    • Cardiac Dysfunction Following Brain Death in Children: Prevalence, Normalization, and Transplantation Article (subscription) – Krishnamoorthy V, Borbely X, Rowhani-Rahbar A, Souter M, et al. (2015) Pediatric Critical Care Medicine, 16(4): e107–e112. https://doi.org/10.1097/PCC.0000000000000397
    • The Effect of a Thyroid Hormone Infusion on Vasopressors Support in Critically Ill Children With Cessation of Neurologic FunctionArticle (subscription) – Zuppa AF, Nadkarni V, Davis L, Adamson PC, et al. (2004) Critical Care Medicine, 32(11):2318-22.
    • Management of the Pediatric Organ Donor to Optimize Lung Donation Article (subscription) – Mallory GB Jr, Schecter MG, Elidemir O. (2009) Pediatr Pulmonol, 44(6):536-46. https://doi.org/10.1002/ppul.20997
    • Management of the Potential Organ Donor in the ICU: Society of Critical Care Medicine/American College of Chest Physicians/Association of Organ Procurement Organizations Consensus Statement Article (subscription) – Muller E. (2015) Transplantation, 99(9):1743. https://doi.org/10.1097/TP.0000000000000896
    • Pediatric Donor Management Goals and Dosing Guidelines Download – Nakagawa TA, (2007) NATCO
    • Process of Organ Donation and Pediatric Donor Management Article (subscription) – Nakagawa, T. and Mou, S. (2011). The Process of Organ Donation and Pediatric Donor Management. Pediatric Critical Care, pp.122-131. https://doi.org/10.1016/B978-0-323-07307-3.10013-8
    • Survey of U.S. Organ Procurement Organizations Regarding Pediatric Organ Donor Management Article (subscription) – Ream RS, Armbrecht ES. (2016) Pediatric Critical Care Medicine, 17(10):e459-e468. https://doi.org/10.1097/PCC.0000000000000912
    • Traumatic Brain Injury in Children, Acute Care Management Download – Geyer K, Meller K, Kuplan C, Mowery BD. (2013) Pediatr Nurs, Nov-Dec;39(6):283-9.
    • Variation in Pediatric Organ Donor Management Practices Among U.S. Organ Procurement Organizations Article (subscription) – Ream RS, Armbrecht ES. (2018) Prog Transplant, 28(1):4-11. https://doi.org/10.1177/1526924817746673. Epub 2017 Dec 15.
    • Vasopressin Pressor Effects in Critically Ill Children During Evaluation for Brain Death and Organ Recovery Article (subscription) – Katz K, Lawler J, Wax J, O’Connor R, Nadkarni V. (2000) Resuscitation, 47(1):33-40.

    OPO Donor Management Protocols

    • Pediatric Donor Management Guidelines – Download – UNYTS
    • Pediatric Organ Donor Management – Download – Donor Network of Arizona
    • Standing Orders for Organ Donor Management – PediatricsDownload – Medical Management to Optimize Donor Organ Potential: A Canadian Forum
  • Pediatric Hospital Order Sets, Checklists, and Trigger Cards

    Resources

    • Pediatric Clinical Trigger CardDownload – Gift of Hope Organ & Tissue Donor Network
    • Neonatal Clinical Trigger Card – Download – Carolina Donor Services
    • Neonatal Clinical Trigger Card – Download – Gift of Hope Organ & Tissue Donor Network
  • Policy Statements and Position Papers

    Academic Journals

    • A Comparison of the Request Process and Outcomes in Adult and Pediatric Organ Donation – Download – Siminoff, L., Molisani, A. and Traino, H. (2015). A Comparison of the Request Process and Outcomes in Adult and Pediatric Organ Donation. Pediatrics, 136(1), pp.e108-e114. https://doi.org/10.1542/peds.2014-3652
    • Expanding the Donor Pool: Regional Variation in Pediatric Organ Donation RatesArticle (subscription) – Godown J, McKane M, Wujcik K, Mettler BA, Dodd DA. (2016) Pediatric Transplant, 20(8):1093-1097. https:/doi.org/10.1111/petr.12779. Epub 2016 Aug 9.
    • Pediatric Organ Donation: A National Survey Examining Consent Rates and Characteristics of Donor HospitalsArticle (subscription) – Webster PA, Markham L. (2009) Pediatric Critical Care Medicine, 10(4):500-4. https:/doi.org/10.1097/PCC.0b013e318198b06b.
    • Pediatric Organ Donation Potential at a Children’s HospitalArticle (subscription) – Bennett EE, Sweney J, Aguayo C, et al. (2015), Pediatric Critical Care Medicine 16(9): 814-820. https://doi.org/0.1097/PCC.0000000000000526.
    • Pediatric Organ Donation: What Factors Most Influence Parent’s Donation Decisions? Article (subscription) – Rodrigue JR, Cornell DL, Howard RJ. (2008) Pediatric Critical Care Medicine, 9(2):180-5. https:/doi.org/10.1097/PCC.0b013e3181668605
    • Policy Statement: Pediatric Organ Donation and Transplantation – Download – Committee on Hospital Care, Section on Surgery, and Section on Critical Care. (2010) Pediatrics, 125(4):822-8. https:/doi.org/10.1542/peds.2010-0081. Epub 2010 Mar 29.
  • Pediatric Reference Lists

    Reference Lists

    • Donation after Circulatory Determination of Death in Children Reference List – Download
    • Pediatric Donor Management Reference List – Download
    • Pediatric Organ Donation Reference List – Download
    • Selected References for Brain Death in Infants and Children – Download
  • Archive
    The archive library contains articles and resources that were originally published 5+ years ago and are no longer current.

    Neonatal & Anencephalic Donation

    • Donation after Cardiac Death: The Potential Contribution of an Infant Organ Donor Population – Article – Labrecque M, Parad R, Gupta M, Hansen A. (2011), J Pediatr, 158(1): 31-36. https://doi.org/10.1016/j.jpeds.2010.06.055. Epub 2010 Aug 21.
    • Identifying Potential Heart Donors Among Newborns Undergoing Circulatory Determination of Death – Article – Mudit M, Castleberry D, Job L. (2011) J Heart Lung Transplant, 30(4): 389-394. https://doi.org/10.1016/j.healun.2010.09.016. Epub 2010 Dec 24.

    Pediatric Determination of Death

    • Clinical Report – Guidelines for the Determination of Brain Death in Infants and Children: An Update of the 1987 Task Force Recommendations – Article – Nakagawa TA, Ashwal S, Mathur M, et al. (2011), Pediatrics, 128(3): e720-740. https://doi.org/10.1542/peds.2011-1511. Epub 2011 Aug 28.
    • Guidelines for the Determination of Brain Death in Infants and Children: An Update of the 1987 Task Force Recommendations – article – Nakagawa TA, Ashwal S, Mathur M, et al. (2011), Crit Care Med, 39(9): 2139-2155. doi:  10.1097/CCM.0b013e31821f0d4f.
    • Pediatric Brain Death Algorithm download
    • Pediatric Catastrophic Brain Injury Guidelines – download
    • Pediatric Devastating Brain Injury Pathway – download – 2008 – University of California-Irvine

    Pediatric Donation After Circulatory Death

    • Development of a Bedside Tool to Predict Time to Death after Withdrawal of Life-Sustaining Therapies in Infants and Children – article – Shore PM, Huang R, Roy L, et al. (2012), Pediatr Crit Care Med, 13(4): 415-422. doi: 10.1097/PCC.0b013e318238b830.

    Checklists

    • Donor Process Checklist- DCD – downloadWisconsin Donor Network

    Policies

    • Donation after Circulatory Death Determination (DCDD) PolicydownloadChildren’s Hospital Pittsburgh

    Pediatric Donor Management

    • Management of the Pediatric Organ Donor – download – Thomas A. Nakagawa, MD Steven S. Mou, MD
    • Management of the Pediatric Organ Donor to Optimize Lung Donation – article – Mallory GB JR, Schecter MG, Elidemir O. (2009), Pediatr Pulmonol 44(6): 536-546. doi:  10.1002/ppul.20997.
    • Pediatric Donor Management Goals and Dosing Guidelines – download – NATCO

    OPO Donor Management Protocols

    • Pediatric Donor Management Guidelinesdownload – Center for Donation and Transplant
    • Pediatric Donor Management – downloadCalifornia Transplant Donor Network
    • Guidelines for Evaluation and Clinical Management of Pediatric Organ Donors – downloadGift of Hope
    • Pediatric Donor Management Goals – downloadLifeSharing of San Diego
    • Pediatric Donor Management Guidelines – downloadIntermountain Donor Services
    • Pediatric Donor Management Guidelines download – LifeLine of Ohio
    • Pediatric Donor Management Made Simple – download – Gift of Life Michigan

    Pediatric Hospital Order Sets and Checklists

    • Pediatric Organ Donation Order SetdownloadDriscoll Children’s Hospital & Southwest Transplant Alliance
    • Guidelines for Pediatric Donor ManagementdownloadIowa Donor Network
    • Guidelines to Initiate Organ Donor Management Pediatric Donor Management OrdersdownloadGift of Life Michigan
    • Pediatric Donor Management Orders Checklist – downloadDonor Network of Arizona
    • Pediatric Donor Management Orders downloadNebraska Organ Recovery Services
    • Pediatric Donor Orders – downloadIntermountain Donor Services
    • Potential Donor Orders (Pediatric) – downloadCarolina Donor Services
    • Pediatric Organ Donor Order Set – downloadTexas Organ Sharing Alliance
    • Pediatric Organ Donor Orders – download – Blood Center of Wisconsin
    • Routine Deceased Donor Orders – PediatricsdownloadLifeShare of the Carolinas
    • Pediatric Levothyroxine Orders download – Texas Organ Sharing Alliance
    • Ventilator Management Orders for Consented Organ Donors – download – LifeShare of the Carolinas

    Donor Checklists

    • Donor Process Checklist – Brain Death – download – Blood Center of Wisconsin

    Policy Statement and Position Papers

    • ASTS Recommended Practice Guidelines for Controlled Donation after Cardiac Death Organ Procurement and Transplantation – article – Reich DJ, Mulligan DC, Abt PL, et al. (2009), Am J Transplant, 9(9): 2004-2011. doi: 10.1111/j.1600-6143.2009.02739.x. Epub 2009 Jul 16.
    • Policy Statement: Pediatric Organ Donation and Transplantation – article – Committee on Hospital Care, Section on Surgery, and Section on Critical Care. (2010), Pediatrics, 125(4): 822-828. doi: 10.1542/peds.2010-0081
    • National Association of Medical Examiners Position Paper on the Medical Examiner Release of Organs and Tissues for Transplantation – article – Pinckard JK, Wetli CV, Graham MA, National Association of Medical Examiners. (2007), Am J Forensic Med Pathol, 28(3): 202-207. 
    • Recommendations for Nonheartbeating Organ Donation. A Position Paper by the Ethics Committee, American College of Critical Care Medicine, Society of Critical Care Medicine – article – Ethics Committee, American College of Critical Care Medicine, Society of Critical Care Medicine. (2001), Crit Care Med, 29(9): 1826-1831.
    • Report of a National Conference on Donation after Cardiac Death – article – Bernat JL, D’Alessandro AM, Port FK, et al. (2006), Am J Transplant, 6(2): 281-291.

Additional Resources Are Available In:

Neurological Determination of Death

Donation after Circulatory Determination of Death

Donor Management

Checklists & Forms