Donor Management

The Alliance welcomes submissions to the Organ Donation Toolbox.
Contributions can be emailed to info@odt-alliance.org with a statement providing approval for posting to this site.

This section has been reviewed and updated as of September 2018. To see past content, click on the Archive tab below.

  • Anesthesia and Operating Room Management
    • Anesthesiologist Donor Management GoalsDownload – Wake Forest University
  • ICU Management

    Blood Products

    • Coagulopathy Thrombobytopenia Guidelines – Download – New England Organ Bank

    Donor Management Goals

    • Current Donor Management Goal Workgroup Bedside Template for Data CollectionDownload – (updated 4-11-14) from Regions 4, 5, and 6

    Endocrine Management

    • Endocrine Function Guidelines – Download
    • Hyperglycemia Management in Organ Donor – Download
    • Polyuria Management in Organ Donor – Download
    • Hypernatremia Decision ToolDownload – New England Donor Services

    Pulmonary Management

    • Lung Donor ManagementDownload – New England Organ Bank
    • Ventilator AutoTriggering Decision ToolDownload – New England Donor Services
    • Lung Management Decision ToolDownload – New England Donor Services

    Overall DM Guidelines and Order Sets

    • Adult Brain Dead Organ Donor Order SetDownload – Center for Organ Recovery & Education
    • Donor Management Guidelines – Download – Midwest Transplant Network
    • Donor Management Guidelines and Protocols for Death by Neurological Criteria – Adults – Download – Legacy of Life Hawai’i
    • Sample Order Set for Hospitals – Download – McLaren Health System
    • Donor Management Goals and Dosing Guidelines – Download – WakeForest University
    • Adult Donor Management Guidelines – Download – Gift of Life Michigan
    • Initial Order Set for Adult Brain Dead DonorsDownload – Gift of Life Michigan
    • Order SetDownload – New England Donor Services
    • Donor Management GuidelinesDownload – New England Donor Services
    • Cardiac Evaluation Decision Tool – Download – New England Donor Services
  • Intensivist Consulting Programs and Models
    • Organ Donation Support Team (ODST) Intensivist Responsibilities – Download – Center for Organ Recovery & Education
    • Organ Donor Support Team (ODST) Donor Data Feedback Form – Download – Center for Organ Recovery & Education
  • Relevant Literature

    Donor Management Goals

    • Determining Optimal Threshold for Glucose Control in Organ Donors after Neurologic Determination of Death: A United Network for Organ Sharing Region 5 Donor Management Goals Workgroup Prospective AnalysisArticle – Sally MB, Ewing T, Crutchfield M, et al. (2014), J Trauma Acute Care Surg, 76(1): 62-68, 69. doi: 10.1097/TA.0b013e3182ab0d9b.
    • ICU Management of the Potential Organ Donor: State of the Art – Article (subscription) – Maciel, C. and Greer, D. (2016). Current Neurology and Neuroscience Reports, 16(9). https://doi.org/10.1007/s11910-016-0682-1
    • Management of the Heartbeating Brain-Dead Organ DonorArticle – McKeown, D., Bonser, R. and Kellum, J. (2012). British Journal of Anaesthesia, 108, pp.i96-i107. https://doi.org/10.1093/bja/aer351
    • Management of the Potential Organ Donor in the ICU: Society of Critical Care Medicine / American College of Chest Physicians / Association of Organ Procurement Organizations Consensus StatementArticle – Kotloff RM, Blosser S, Fulda GJ, et al. (2015), Crit Care Med, 43(6): 1291-1325. doi: 10.1097/CCM.0000000000000958.
    • Organ Donation in Adults: A Critical Care PerspectiveArticle (subscription) – Citerio, G., Cypel, M., Dobb, G., Dominguez-Gil, B., Frontera, J., Greer, D., Manara, A., Shemie, S., Smith, M., Valenza, F. and Wijdicks, E. (2016). Intensive Care Medicine, 42(3), pp.305-315. https://doi.org/10.1007/s00134-015-4191-5
    • The Impact of Meeting Donor Management Goals on the Development of Delayed Graft Function in Kidney Transplant Recipients – Article – Malinoski DJ, Patel MS, Ahmed O, et al. (2013), Am J Transplant, 13(4): 993-1000. doi: 10.1111/ajt.12090. Epub 2013 Feb 13.

    Endocrine Management

    • Comparison of High- and Low-Dose Corticosteroid Regimens for Organ Donor Management – Article – Dhar R, Cotton C, Coleman J, et al. (2013), J Crit Care, 28(1): 111.e1-7. doi: 10.1016/j.jcrc.2012.04.015. Epub 2012 Jul 2.

    Renal Management

    • Impact of a Quality Improvement Project on Deceased Organ Donor ManagementArticle – Olmos A, Feiner J, Hirose R, et al. (2015), Progress in Transplantation, 25(4): 351-360. doi: 10.7182/pit2015129.
    • Therapeutic hypothermia in deceased organ donors and kidney-graft function.Article – Nieman CU, Feiner J, Swain S, et al. (2015), N Engl J Med, 373(5): 405-414.
  • Archive

    ICU Management

    Overall DM Guidelines and Order Sets

    • Donor Management GuidelinesDownloadOneLegacy
    • Donor Patients – Adult, Order SheetDownload – Dartmouth-Hitchcock Medical Center / New England Organ Bank
    • Standard Orders for BD Donors – DownloadOneLegacy

    Pulmonary Management

    Intensivist Consulting Programs and Models

    • Organ Donation Support Team (ODST) Intensivist Responsibilities – Download – Center for Organ Recovery & Education
    • Intensivist Role and Interactions (in Organ Donation) Policy – Download – Midwest Transplant Network
    • Intensivist-Led Management of Brain-Dead Donors Is Associated with an Increase in Organ Recovery for Transplantation – Article – Singbartl K, Murugan R, Kaynar AM, et al. (2011), Am J Transplant, 11(7): 1517-1521. doi: 10.1111/j.1600-6143.2011.03485.x. Epub 2011 Mar 30.
    • Organ Donor Support Team (ODST) Donor Data Feedback Form – Download – Center for Organ Recovery & Education

    Relevant Literature

    Blood Products

    • Clinical Practice Guideline: Red Blood Cell Transfusion in Adult Trauma and Critical CareArticle – Napolitano LM, Kurek S, Luchette FA, et al. (2009), Crit Care Med, 37(12): 3124-3157. doi: 10.1097/CCM.0b013e3181b39f1b.

    Cardio and Hemodynamic Management

    • Consensus Conference Report: Maximizing Use of Organs Recovered from the Cadaver Donor: Cardiac Recommendations – Article Zaroff JG, Rosengard BR, Armstrong WF, et al. (2002), Circulation, 106(7): 836-841.

    Donor Management Goals

    • Achieving Donor Management Goals Before Deceased Donor Procurement is Associated with More Organs Transplanted per Donor – Article – Malinoski DJ, Daly MC, Patel MS, et al. (2011), J Trauma, 71(4): 990-995, 996. doi: 10.1097/TA.0b013e31822779e5.
    • Medical Management to Optimize Donor Organ Potential: Review of the Literature – Article – Kutsogiannis DJ, Pagliarello G, Doig C, et al. (2009), Can J Anaesth, 53(8): 820-830.
    • Optimization of Donor Management Goals Yields Increased Organ Use – Article – Franklin GA, Santos AP, Smith JW, et al. (2010), Am Surg, 76(6): 587-594.
    • Recommendations for End-of-Life Care in the Intensive Care Unit: A Consensus Statement by the American Academy of Critical Care MedicineArticle – Truog RD, Campbell ML, Curtis R, et al. (2008), Crit Care Med, 36(3): 953-963. doi: 10.1097/CCM.0B013E3181659096.
    • Review of Randomized Clinical Trials of Donor Management and Organ Preservation in Deceased Donors: Opportunities and Issues. Article – Dikdan GS, Mora-Esteves C, Koneru B. (2012), Transplantation, 94)5): 425-441. doi: 10.1097/TP.0b013e3182547537.
    • The Impact of Meeting Donor Management Goals on the Number of Organs Transplanted per Donor: Results from the United Network for Organ Sharing Region 5 Prospective Donor Management Goals Study – Article – Malinoski DJ, Patel MS, Daly MC, et al. (2012), Crit Care Med, 40(10): 2773-2780. 

    Endocrine Management

    • Glycemic Control and Organ Transplantation – Article – Marvin MR, Morton V. (2009), J Diabetes Sci Technol, 3(6): 1365-1372.
    • The Impact of Early Hormonal Therapy in Catastrophic Brain-Injured Patients and its Effect on Organ ProcurementArticle – Lam L, Inaba K, Branco BC, et al. (2012), Am Surg, 78(3): 318-324.

    Hormone Replacement

    • A Systematic Review and Meta-Analysis of Clinical Trials of Thyroid Hormone Administration to Brain Dead Potential Organ Donors – Article – Macdonald PS, Aneman A, Bhonagiri D, et al. (2012), Crit Care Med, 40(5): 1635-1644. doi: 10.1097/CCM.0b013e3182416ee7.
    • Relationship of Hormonal Resuscitation Therapy and Central Venous Pressure on Increasing Organs for Transplant – Article – Abdelnour T, Rieke S. (2009), J Heart Lung Transplant, 28(5): 480-485. doi: 10.1016/j.healun.2009.01.018.
    • The Haemodynamic Effects of Adjunctive Hormone Therapy in Potential Heart Donors: A Prospective Randomized Double-Blind Factorially Designed Controlled Trial – Article – Venkateswaran RV, Steeds RP, Quinn DW, et al. (2009), Eur Heart J, 30(14): 1771-1780. doi: 10.1093/eurheartj/ehp086. Epub 2009 Mar 26.

    Pulmonary Management

    • Airway Pressure Release Ventilation and Successful Lung Donation – Article – Hanna K, Seder CW, Weinberger JB, et al. (2011), Arch Surg, 146(3): 325-328. doi: 10.1001/archsurg.2011.35.
    • Airway Pressure Release Ventilation During Adult Donor Care – Article – Powner DJ, Graham R. (2010), Prog Transplant, 20(3): 269-273.
    • Effect of a Lung Protective Strategy for Organ Donors on Eligibility and Availability of Lungs for Transplantation: A Randomized Controlled TrialArticle – Mascia L, Pasero D, Slutsky AS, et al. (2010), JAMA, 304(23): 2620-2627. doi: 10.1001/jama.2010.1796.
    • Pulmonary Recruitment Protocol for Organ Donors: A New Strategy to Improve the Rate of Lung Utilization – Article – Noiseux N, Nguyen BK, Marsolais P, et al. (2009), Transplant Proc, 41(8): 3284-3289. doi: 10.1016/j.transproceed.2009.08.041.
    • Recommendations for Mechanical Ventilation During Donor Care – Article – Powner DJ, Darby JM, Stuart SA. (2000), Prog Transplant, 10(1): 33-38, quiz 39-40.

    Renal Management

    • Donor Dopamine Pretreatment and Graft Function After Kidney Transplantation – Comments and Replies on “Effects of Donor Pretreatment with Dopamine on Graft Function after Kidney Transplantation: A Randomized Controlled Trial” – Article – Ball J, McAnulty G. (2010), JAMA, 303(3): 231, author reply 231-232. doi:  10.1001/jama.2009.1996.
    • Donor Dopamine Pretreatment and Graft Function After Kidney Transplantation – Comments and Replies on “Effects of Donor Pretreatment with Dopamine on Graft Function after Kidney Transplantation: A Randomized Controlled Trial” – Article – Ridgway D, Barrie J, Menon K. (2010), JAMA, 303(3): 230-232. doi: 10.1001/jama.2009.1995.
    • Donor Dopamine Pretreatment and Graft Function After Kidney Transplantation – Comments and Replies on “Effects of Donor Pretreatment with Dopamine on Graft Function after Kidney Transplantation: A Randomized Controlled Trial” – Article – Silverstein JH. (2010), JAMA, 303(3): 230, author reply 231-232. doi: 10.1001/jama.2009.1994.
    • Effect of Donor Pretreatment with Dopamine on Graft Function After Kidney Transplantation: A Randomized Controlled Trial – Article – Schnuelle P, Gottmann U, Hoeger S, et al. (2009), JAMA, 302(10): 1067-1075. doi: 10.1001/jama.2009.1310.
    • Predictors Associated with Terminal Renal Function in Deceased Organ Donors in the Intensive Care Unit – Article – Blasi-Ibanez A, Hirose R, Feiner J, et al. (2009), Anesthesiology, 110(2): 333-341. doi: 10.1097/ALN.0b013e318194ca8a.

    Other

    • Incremental Increases in Organ Retrieval after Protocol Driven Change in an Organ Procurement Organization: A 15-Year Assessment – Article – Franklin GA, Smith JW, Daugherty W, et al. (2009), Am Surg, 75(7): 537-543, discussion 543-544. 

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