Catastrophic Brain Injury Guidelines

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This section has been reviewed and updated as of August 2018. To see past content, click on the Archive tab below.

  • Adult


    • Trauma ICU Catastrophic Brain Injury Guidelines and Order SetDownload – Oregon Health & Science University
    • Adult Catastrophic Brain Injury Order Set – Download– – Sunrise Hospital and Medical Center
  • Literature

    Academic Journals

    • Active Donor Management During the Hospital Phase of Care Is Associated with More Organs Transplanted per Donor Article (subscription) – Patel, M., De La Cruz, S., Sally, M., Groat, T. and Malinoski, D. (2017). Journal of the American College of Surgeons, 225(4), pp.525-531.
    • Deceased Organ Donor Management: Does Hospital Volume Matter?Article (subscription) – Patel, M., Mohebali, J., Sally, M., Groat, T., Vagefi, P., Chang, D. and Malinoski, D. (2017). Journal of the American College of Surgeons, 224(3), pp.294-300,
    • The Development and Current Status of Intensive Care Unit Management of Prospective Organ DonorsArticle – Ellis, M. K. M., Sally, M. B., & Malinoski, D. (2016). Indian Journal of Urology : IJU : Journal of the Urological Society of India, 32(3), 178–185.
    • Differential Effects of Intraoperative Positive End-expiratory Pressure (PEEP) on Respiratory Outcome in Major Abdominal Surgery Versus Craniotomy Article – De Jong, M., Ladha, K., Melo, M., Staehr-Rye, A., Bittner, E., Kurth, T. and Eikermann, M. (2016).  Annals of Surgery, 264(2), pp.362-369.
    • The Effect of an Intraoperative, Lung-Protective Ventilation Strategy in Neurosurgical Patients Undergoing Craniotomy: Study Protocol for a Randomized Controlled Trial Article – Zhang, L., Xiong, W., Peng, Y., Zhang, W. and Han, R. (2018). Trials, 19(1).
    • Emergency Department Referral for Organ Donation: More Organ Donors and More Organs Per Donor – Article (subscription) – Miller, L., Gardiner, S. and Gubler, K. (2014). The American Journal of Surgery, 207(5), pp.728-734.
    • Hypocalcemic Myocardial Dysfunction: Short- and Long-Term Improvement With Calcium Replacement Article (subscription) – Wong, C., Lau, C., Cheng, C., Leung, W. and Freedman, B. (1990). American Heart Journal, 120(2), pp.381-386.
    • ICU Management of the Potential Organ Donor: State of the ArtArticle (subscription) – Maciel, C. and Greer, D. (2016). Current Neurology and Neuroscience Reports, 16(9).
    • Impact of Catastrophic Brain Injury Guidelines on Donor Management Goals at a Level I Trauma Center – Article (subscription) – Quinn, L., McTague, W. and Orlowski, J. (2012). Transplantation Proceedings, 44(7), pp.2190-2192. https://10.1016/j.transproceed.2012.07.112
    • Intraoperative Fluid Management: Past and future, Where is the Evidence?Article (subscription) – Al-Ghamdi, A. (2018). Saudi Journal of Anaesthesia, 12(2), p.311.
    • Low Albumin Levels, More Than Morbid Obesity, Are Associated With Complications After TKAArticle – Nelson, C., Elkassabany, N., Kamath, A. and Liu, J. (2015). Clinical Orthopaedics and Related Research®, 473(10), pp.3163-3172.
    • Management of the Heart Beating Brain-Dead Organ DonorArticle – McKeown, D., Bonser, R. and Kellum, J. (2012). British Journal of Anaesthesia, 108, pp.i96-i107.
    • Management of the Potential Organ Donor in the ICUArticle (subscription) – Kotloff, R., Blosser, S., Fulda, G., et al. (2015). Critical Care Medicine, 43(6), pp.1291-1325.
    • Minimally Invasive Measurement of Cardiac Output during Surgery and Critical CareArticle – Peyton, P. and Chong, S. (2010). Anesthesiology, 113(5), pp.1220-1235.
    • Organ Donation in Adults: A Critical Care PerspectiveArticle (subscription) – Citerio, G., Cypel, M., Dobb, G., Dominguez-Gil, B., Frontera, J., Greer, D., Manara, A., Shemie, S., Smith, M., Valenza, F. and Wijdicks, E. (2016). Intensive Care Medicine, 42(3), pp.305-315.
    • A Prospective Comparison of a Noninvasive Cardiac Output Monitor Versus Esophageal Doppler Monitor for Goal-Directed Fluid Therapy in Colorectal Surgery PatientsArticle (subscription) – Waldron, N., Miller, T., Thacker, J., Manchester, A., White, W., Nardiello, J., Elgasim, M., Moon, R. and Gan, T. (2014). Anesthesia & Analgesia, 118(5), pp.966-975.
  • Archive
    The archive library contains articles and resources that were originally published 5+ years ago and are no longer current.


    • Catastrophic Brain Injury Guidelines – Download – (2011)
    • Severe Brain Injury Support Orders for Age 16 and Above – Download – 2009 – St. Josephs Hospital


    • Aggressive Organ Donor Management Protocol – Article – DuBose J, Salim A. (2008), J Intensive Care Med, 23(6): 367-375. doi: 10.1177/0885066608324208.
    • Care of the Potential Organ Donor – Article (subscription) – Wood KE, Becker BN, McCartney JG, et al. (2004), N Engl J Med, 351: 2730-2739. https:/
    • Devastating Brain Injuries- Assessment and Management Part 1: Overview of Brain Death – Article – Dixon TD, Malinoski DJ. (2009), West J Emerg Med, 10(1): 11-17.
    • Impact of Compliance with the American College of Surgeons Trauma Center Verification Requirements on Organ Donation-Related Outcomes – Article – Malinoski DJ, Patel MS, Lush S, et al. (2012), J Am Coll Surg, 215(2): 186-192. doi: 10.1016/j.jamcollsurg.2012.03.011. Epub 2012 May 23.