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Neurologic Determination of Death

Link to Determination of Death laws for each state by visiting this link and clicking on the State Determination of Death Laws tab –  “Legal & Regulatory References“.

  • Brain Death ToolkitACCESS (The Alliance recommends and endorses referencing the Brain Death Toolkit hosted by the Neurocritical Care Society for all Neurological Determination of Death related references and resources.)
  • Brain Death Examination – Online Learning Module – link to – Death by Neurological Criteria Module, Cleveland Clinic
  • Evidence-Based Guideline Update: Determining Brain Death in Adultsarticle – Wijdicks EFM, Varelas PN, Gronseth GS, Greer DM. (2010), Neurology, 74: 1911-1918.

Other Relevant Literature 

  • A Review of Ancillary Tests in Evaluating Brain Death – article – Heran MK, Heran NS, Shemie SD. (2008), Can J Neurol Sci, 35(4): 409-419.
  • American Academy of Neurology Guidelines and the Neurologic Determination of Deatharticle – Rady MY, Verheijde JL. (2016), JAMA Neurol, 73(6): 760-761. doi: 10.1001/jamaneurol.2016.0428 NEW!
  • Brain death and Transcranial Doppler: Experience in 130 Cases of Brain Dead Patients – article – Ducrocq X, Braun M, Debouverie M, et al. (1998), J Neurol Sci, 160(1): 41-46.
  • Brief Review: The Role of Ancillary Tests in the Neurological Determination of Death – article – Young GB, Shemie SD, Doig CJ, Teitelbaum J. (2006), Can J Anaesth, 53(6): 620-627.
  • Computed Tomography Angiography in the Diagnosis of Brain Death: A Systematic Review and Meta-analysis – article – Kramer AH, Roberts DJ. (2014), Neurocrit Care, 21(3): 539-550. doi: 10.1007/s12028-014-9997-4. NEW!
  • Family Presence During Brain Death Evaluation article – Tawil I, Brown LH, Comfort D, et al. (2014), Crit Care Med, 42(4): 934-42. doi: 10.1097/CCM.0000000000000102.
  • Guidelines for the Determination of Brain Death in Infants and Children: An Update of the 1987 Task Force Recommendations – article – Nakagawa TA, Ashwal S, Mathur M, et al. (2011), Pediatrics, 128(3): e720-e740. doi: 10.1542/peds.2011-1511.
  • Impact of a Computerized Note Template/Checklist on Documented Adherence to Institutional Criteria for Determination of Neurologic Death in a PICU – article – Stockwell JA, Pham N, Fortenberry JD. (2011), Pediatr Crit Care Med, 12(3): 271-276. doi: 10.1097/PCC.0b013e3181fe27da.
  • Predictors of Apnea Test Failure During Brain Death Determination – article – Yee AH, Mandrekar J, Rabinstein AA, Wijdicks EF. (2010), Neurocrit Care, 12(3): 325-355. doi: 10.1007/s12028-010-9343-4.
  • Pronouncing Brain Death: Contemporary Practice and Safety of the Apnea Test – article – Wijdicks EF, Rabinstein AA, Manno EM, Atkinson JD. (2008), Neurology, 71(16): 1240-1244. doi: 10.1212/01.wnl.0000327612.69106.4c.
  • Scintigraphy as a Confirmatory Test of Brain Death – article – Conrad GR, Sinha P. (2003), Semin Nucl Med, 33(4): 312-323.
  • Transcranial Doppler Ultrasonography to Confirm Brain Death: a Meta-Analysis – article – Monteiro LM, Bollen CW, van Huffelen AC, et al. (2006), Intensive Care Med, 32(12): 1937-1944. Epub 2006 Sept 21.