DNA Scoring System Could Improve Kidney Transplant Matching

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Doctors currently rely on several criteria including three main blood tests, cell surface tests and limited DNA tests to determine if a patient and a potential donor are a kidney match.

But the system is far from flawless. While transplant survival rates for patients with end stage renal failure are higher than for those treated with dialysis, 40% to 50% of kidney transplants still fail within 10 years.

Now scientists have come up with a comprehensive DNA scoring system using many genes to predict long-term success of transplantation. This new system is described in a study published in PLOS Computational Biology.

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