Education Corner – Developing Advances in Organ Transplantation: Organ Banking – What is it?

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Developing Advances in Organ Transplantation: Organ Banking – What is it?

A New World?

Imagine a world where no one who needs an organ transplant has to wait for an organ to become available. A transplant in this new world would be a scheduled surgery. Families who want the donation process to occur quickly could easily be accommodated, as the organs can be recovered and banked until the right ...

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Virtual Journal Club: To Presume Consent or Not to Presume Consent?

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To Presume Consent or Not to Presume Consent? What does the data show? Comparing Organ Donation Rates in “Opt-In” vs. “Opt-Out” Systems

Thomas Mone, MS; CEO OneLegacy, Los Angeles, 2017

Introduction:
Almost every day, somewhere in the world, a news headline calls for countries to adopt Opt-Out organ donation policies. Accompanying the call-to-action, is often a heart-wrenching story of a young child desperately awaiting a lifesaving transplant, or recipients seeking the help of their legislators to modify laws ...

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Nanoparticles “trick” body into accepting organ transplants

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Using nanoparticles, Yale researchers have developed a drug-delivery system that could reduce organ transplant complications by hiding the donated tissue from the recipient’s immune system.

About 25,000 organ transplants are performed in the U.S. each year. Despite significant advances in the field, short-term and long-term organ rejection still poses a risk (rejection rates vary depending on the type of organ). The risk of rejection is even higher when the donor is deceased, due to organ damage.

T cells, the white blood cells ...

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Novel procedure improves kidney transplant success

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A new treatment might open the door for more patients with advanced kidney disease to get a transplant, a preliminary study suggests.

Of the 100,000-plus Americans waiting for a donor kidney, about one-third are “sensitized,” said Dr. Robert Montgomery, director of the Transplant Institute at NYU Langone in New York City.

Those patients face a tough situation: They harbor immune system antibodies that are primed to attack a donor organ.

The antibodies can form when a person is ...

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Liver transplant patients benefit from moderate, high intensity exercise

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Combined resistance and aerobic training at moderate to high intensity improved aerobic capacity, maximal strength and health-related quality of life in liver transplant patients, according to a recently published study.

“An adequate recovery together with an improvement in the patient fitness and indirect understanding of the relevance of exercise in [health-related quality of life] may result in the long-term in a reduced incidence of metabolic complications,” Diego Moya-Nájera, MsC, from the University of Valencia, Spain, and colleagues wrote. “Indeed, diseases associated with metabolic ...

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Pros and Cons: Infecting patients with hepatitis C to save their lives

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Around the country, physicians have begun transplanting HIV-positive organs into HIV-positive patients, thanks to the reversal in 2013 of a 1998 law that banned their use. And it has become standard for transplant centers to give hep C–positive organs to patients who already have a hep C infection. Now doctors have crossed a medical threshold—and an ethical one: giving infected kidneys and livers to people who had no trace of hep C to help them get an organ ...

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Engineered liver tissue expands after transplant

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Many diseases, including cirrhosis and hepatitis, can lead to liver failure. More than 17,000 Americans suffering from these diseases are now waiting for liver transplants, but significantly fewer livers are available.

To help address that shortage, researchers at MIT, Rockefeller University, and Boston University have developed a new way to engineer liver tissue, by organizing tiny subunits that contain three types of cells embedded into a biodegradable tissue scaffold. In a study of mice with damaged livers, the researchers found that ...

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HRSA announces record-breaking hospital campaign results

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The U.S. Department of Health and Human Services has released the results of the 2017 Workplace Partnership for Life Hospital Organ Donation Campaign. More than 1,000 hospitals and transplant centers, including 296 small and rural hospitals, earned platinum, gold, silver or bronze recognition for their outstanding efforts to promote donation awareness and donor registration between October 2016 and April 2017. The Campaign which unites hospitals, healthcare associations, organ procurement organizations, and Donate Life America affiliates to work together to increase ...

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Eighteen months after double hand transplant, child is now able to write, and feed and dress himself independently

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The world’s first double hand transplant in a child has been successful under carefully considered circumstances. The study, which is published in The Lancet Child & Adolescent Health journal, presents the first medical report of the surgery and 18 months of follow-up.

The recipient of the transplant was an 8-year-old boy based in the USA, who is now able to write, and feed and dress himself independently following months of occupational therapy and psychological support.

However, during this time ...

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Opioid epidemic leads to more organ donors, transplants across the country

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In a rising tide of tragedy with no end in sight, figures through half of this year point to another record year of opiod-related deaths across the country in 2017.

The number of organ donors who died of overdoses more than doubled across the country from 625 in 2014 to 1,263 in 2016, and is projected to rise to about 1,400 this year, according to federal data. That same data shows that most of that increase came from Appalachian states like ...

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