Innovation

Mom, son make history with live liver donation assisted by 3D printing

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SALT LAKE CITY – Nearly 14,000 people are on the liver transplant list, according to the American Liver Foundation. Experts say about 10% of them will die or become too sick for transplant before it’s their turn.

This is the story of a Salt Lake City mother and son. She gave him life, and now he is doing the same. It’s a surgery with a unique twist.

Gwen Finlayson’s autoimmune hepatitis led to cirrhosis years ...

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UW Launches Nation’s First Cell Therapy Trial for Kidney Transplant Patients

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From UW Health: For the first time in the United States, a research team will test a personalized cell therapy to treat a common and serious complication facing kidney transplant patients.

The UW Program for Advanced Cell Therapy (PACT) will study a cutting-edge therapy to treat a viral infection faced by around 30 to 40 percent of kidney and/or pancreas transplant recipients.

The study will deploy virus-specific white blood cells to treat severe cytomegalovirus (CMV) infection after kidney transplantation.

The Federal Drug Administration-approved trial will begin ...

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A Statement from The Alliance regarding President Trump’s Executive Order on July 10, 2019

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Dr. John Magee (Alliance Board Chair, left) and Kevin O’Connor (Alliance Board Vice Chair, right) were pleased to be in attendance last week during President Trump’s announcement of an executive order to enhance kidney care and improve donation and transplantation.

As shared by Dr. Magee, “The Alliance supports any effort to increase organ donation and transplantation. Health care always involves rigorous assessment and continuous efforts to improve. The Alliance looks forward to continuing our efforts in this important undertaking through our ...

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Baby gets liver transplant using 4K/3D technology

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From The Miami Times: UHealth surgeons at Holtz Children’s Hospital are first in the world to use this innovative technology for transplantation, which magnifies images 26 times leading to better outcomes for high-risk patients.

Michael David Antonio Angelo was born healthy in September 2018. During his first two months of checkups with his pediatrician, he was given a clean bill of health. But soon after, his mother started noticing her baby boy’s skin had a yellow tone, also known as jaundice. ...

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UC Health performs first liver transplant in US using mobile cold perfusion pump

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Transplant surgeons at UC Health’s University of Cincinnati (UC) Medical Center have performed the first-ever liver transplant in the United States with an organ preserved using portable hypothermic machine perfusion. The technology, which had been under development for several years, is designed to circulate a specially formulated, cold-temperature medical solution throughout a donor liver during its journey from the point of donation to surgical transplantation into a recipient.

This “active” preservation device was invented to improve upon traditional “static” cold preservation, ...

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Hepatitis C not a barrier for organ transplantation, study finds

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From NPR science correspondent Richard Harris:

Donated organs from people who were infected with the hepatitis C virus can be safely transplanted, according to the latest in a line of studies that are building a case for using these organs.

Typically, these organs have been discarded because of concerns about spreading the viral infection. But a study of heart and lung transplants published Wednesday by the New England Journal of Medicine finds that new antiviral drugs are so effective that the recipients ...

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US begins organ transplants from living donors with HIV

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WASHINGTON (AP) — Surgeons in Baltimore have performed what’s thought to be the world’s first kidney transplant from a living donor with HIV, a milestone for patients with the virus who need a new organ — and one that could free up space on the transplant waiting list for everyone.

Nina Martinez of Atlanta traveled to Johns Hopkins University to donate a kidney to [another patient living with HIV], saying she “wanted to make a difference in somebody else’s life” and ...

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Fluorescing urine signals organ transplant rejection, could replace needle biopsies

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Glowing urine may replace the biopsy needle: In detecting organ transplant rejection, a new nanoparticle has proven much faster and more thorough in the lab than a biopsy. When T cells mount their first attack on the organ’s cells, the nanoparticle sends an alarm signal into the urine that makes it fluoresce.

Too often, it’s only after a transplanted organ has sustained serious damage that a biopsy reveals the organ is in rejection. A new screening method using sensor particles and ...

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Could Blood Test Predict Lung Transplant Rejection?

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Note: Check out our recent webinar on this topic: “Detecting Rejection Without Biopsies: Are We There Yet?”

A novel blood-based biomarker of lung transplant dysfunction in newly transplanted lungs could help identify patients at high risk for chronic rejection without a lung biopsy, researchers reported.

In what was characterized as a proof-of-concept study, researchers from the National Heart, Lung, and Blood Institute (NHLBI), Johns Hopkins School of Medicine, and several other institutions described how donor-derived cell-free DNA (%ddcfDNA) characterized “post-transplantation ...

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First baby born to woman with uterus transplanted from deceased donor

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For the first time, a baby has been born to a woman who received a uterus transplant from a deceased donor, according to Hospital das Clínicas at the University of São Paulo School of Medicine in Brazil.

The Brazilian team followed protocols established by Dr. Mats Brännström and his team at the University of Gothenburg in Sweden, where the first successful uterus transplant, that one from a living donor, was performed in 2013. That recipient mother gave birth in 2014.

The donor, a 45-year-old ...

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